The first baby created from an egg matured in the lab, frozen, thawed and then fertilised, has been born.
Until now it was not known whether eggs obtained in this way could survive thawing to be fertilised.
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Canadian researchers told a fertility conference in Lyon three others were expecting babies by the same process.
Why is this important?
The advance spares women from taking risky fertility drugs that can cause a rare, yet deadly condition - ovarian hyperstimulation syndrome (OHSS).
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The findings hold particular hope for patients with cancer-related fertility problems.
Chemotherapy can cause infertility and, therefore, some women with cancer opt to have their eggs collected and frozen before they start their cancer treatment.
But not all women will want or be able to delay having chemotherapy to undergo ovarian stimulation.
Certain tumours, including some breast cancers, can grow if the woman takes drugs to stimulate the ovaries, for example.
Although one of the doctors involved cautioned that the technique hadn't yet been tried on women with cancer.
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